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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17d17a16e3f2e032cbeefe4dd4eb3f67a1b67050f65451bb4751da3509151c12' 
  AND token = '6QcVdviOCOeMu8eCl1l7pMgsjXLSiKCwdh3yMTuzT7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}