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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cd19fa9d36be520bc3fcfc6f1160724819bb6de200dbc4be0ba5c2918e9288e' 
  AND token = 'HU2vL1z8S813JG2blrTarYkeW5GESdFD4wFmXTw8AU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}