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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed0886bc0c9ec48d20c452ed8b8e3d92a4807bd10b3eb8d134ec48905cb194a' 
  AND token = 'lBt9ch4iiJ3RjrJo0SRexRbsoSOMqHx8o6p0x2JHFJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}