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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e246f1884061903140ab0fff28a1a3069d835fe46f2f3a78df2e5902b21a515' 
  AND token = 'J1bsrXRPOQXGcDbnF7tBAFkiyTpiE5WUVKk1s43TYAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}