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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ade205ef220612e3dfed0e5972dcd56d97430fae8bb35e07e62aa98df25e2d0b' 
  AND token = '/AwtNYmZKR3s9mSmr5NhU8Ena4Y/ZsfvUrVr6mXpnPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}