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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b53db81de9ab9f11f688adf67814b6d42530bc2c290babe0940df5a0666e68b' 
  AND token = 'uuWUlhervTqT+hTNTIKeqJ8Ovt4jVoN8cSmen+r2DE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}