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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f3f915e2f25537209ee7b339c4231971b6912ecb03bc769ffc546734e38ef4' 
  AND token = 'It5DmiQb4kqlEbs2JkN4z+w/YzSBiE+Q2cde/bq2HlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}