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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3c080b4c483ea6504d41d20c125754a264eb8f188477b5f7fc92ad23d4ec2ca' 
  AND token = '12vdh7lDEJmLQKMVZkz/R4p2S3r63c5p0oTz27j3S9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}