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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f01c4535cf7cab4f81509230e56236565ecd462605aca676dd16d6745b6e6c' 
  AND token = 'eTp+igb0b8Esj6+hpov0im2wJYXOXwluKYRtjwpajNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}