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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cee6b0c45e634a6478c47d9350441b5274ae7054516c0cfac66127d7cc56603' 
  AND token = 'DUvQbUWv95U8CU2PO3aDNBOwVjuDojgdxaklqqZYTj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}