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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c2549932570596355aa7ce12d0e076f2380827dd2a7c87192b6f1a8d6c7a37f' 
  AND token = 'PZ3cswm07mK1p14XNrhOFqAyK2uy11bGAxO6pLoiHpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}