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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff801a0423067e5b9bfe6d9a5928b713d80fe5d58cb3238a4cb89dead1b450ed' 
  AND token = 'yPpoT78XpQ6Mm1zVVMWed5y0bdv6BefJ8heSm9G3fqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}