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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '718b89be8a374a78db142d76406696d59ddec261f7b229bd49e8b53cbea6ee14' 
  AND token = 'bV4bUsPGVjn4rosfrk+pECk9HragaOy1bkP0gY/Qs6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}