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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99638277a3165032b8a4865e2b5d3297f1bfc98ee2c007c3b12abeee4984fdaf' 
  AND token = '49cXdBbuyzR6RESRjTTRa6OpB31gvykUmlj4re2rmP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}