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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3a0cb8bfdccd3d2d162b36a827180db417d47e0d9cd7669af3882ffa11e81ec' 
  AND token = 'Gyxn66749Q8UzaaBKB3z9VKNlhXRaoIp4TDmACea/GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}