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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78cc90e2b8a665ec2db89c76ae40942317c4099ccf992fe1e58ce3b192df6fb8' 
  AND token = '9SX4a0K5fLq2UihFGba1csGx0LyHdMhkWjuwhfYqRDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}