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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2633c7a800d0ba8025b7303c32afd0100f85b348f4b4feb023a093d6d47d448b' 
  AND token = '3YnYFFtf0v7gDlOd9b4uj8DBHK9IyKkFmvzDcomxWWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}