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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df1d294dde94f349ac198d041054104f5aecc1e0c4142f51c1cd279f1a0cbcf6' 
  AND token = 'KIgkI2gA32zaeHwKU3VU71hCE0pYU6K17vJdwR3IWqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}