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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f72c77daf93973b47e458081dbabc85c2fe37434c7f57918c78eed73476737c' 
  AND token = 'yChW/xS2HzGk6I/zReiEDqIkEMlOqym2qEQUwbJdXsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}