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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '358a36b4e21e383f92d5a1a44c82b31b18ef05b934af130c633045062048cacb' 
  AND token = '/st3S/ejO96vPl0T2hi9G1wv9LRdRW8nd1Xdn2aoCy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}