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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba7b49c2ceff9368c5de04cc65ecd4d2312f63276a5f1f27df35ebef3890ca69' 
  AND token = 'LsTZZVbga8lZXjXBMgrUI4EJM4ReGwMWC7kpScV/AnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}