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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ec208b318a691e83b3e2c925b170c3fe4cb023003b5f6efa57ed50c51374e9c' 
  AND token = 'J3/oHSI5PL3UDExYCLGgPggoao+ljkgeZyrlho0Y+Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}