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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec8a5f654e4c386a00be5404a8e42cb0d85ea7139452057885e943cfce23d7e3' 
  AND token = 'sLucpRor9bFXlOwWMwuVOVBB1rgu4+Y0vK0QxMBmuLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}