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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78763e98e4f2d9f56d2206c35d221917161fc6beb1350393dbb4dc5bedc775aa' 
  AND token = '0VyBH5LHDsKKXb2ePTlDB9ORxRnDIaAsiWaj2wCIl70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}