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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95b396dd59fa337958767bbf2e35c6a4b70cc318a8ccf8c30f1ac9d86c6da649' 
  AND token = 'Aw25ktYGvtaixSXR3zj/CiAU1+MACsrjyfZOUL9o4NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}