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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c92459640064bcbd69c41cd07e2228bcf404168a9255d5e929ee35e629af9e4' 
  AND token = 'yF27eRU3kq/ngD+HT2sad1qisMALx1tDILKtVibenGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}