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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708cf2f64c3aeffe4b2f78f290119e5f09d248644de7424d13375ddb5239297d' 
  AND token = 's7hgdwxnCFyHOkH2JoRASKZ3HkcANoB9lL4pmwPC1z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}