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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a844765e5b837be2e64e9faed6b08d1b4c7af8e89f9424712174b11b864b49a' 
  AND token = '/9wsCBLiZUfHMjiqh8xzWSnOZj741higoxMSb5sxg8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}