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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a53fbe70ec693d4ddf73150de443da3fbb50e96a091407910010b3fb99c106' 
  AND token = 's3ShFeddwvdvBXZoDz8/ooStTRdL2OL69Z3tsKplyTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}