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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd95e0e9f67f0e6ae351b6491edfb63157043a50033e8d7e95875dfd43e8807bb' 
  AND token = 'Id7ro6Ia+3MG7wUZSfKWcccTnJXq4P/0UimtlVHLSvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}