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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '948b076f5d18f9fa1857d05245ae817a8cd2463e76bc03d8e671e74eca0d83ce' 
  AND token = 'guu/hF4g6HoqE7bQTo+dWD0r3zFG3FqQjNDWzRRfPTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}