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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d383a4925a03726f706027b0202a39b351fae45f6756d6b8672ec386eb64edf' 
  AND token = 'EDePWmAZwalYgnE3KQDIx93qrsuzPrzHWK6djid80zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}