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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e12475ac1ba24e9ed7bb9fd25e9ac73eefe3a24a8da6d4f6344d68d35f6f61f' 
  AND token = 'Stfyz9F21pXJaC+megAgprtl+bwNRmfLKIoyqSst0So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}