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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f7df69f79cd1db77159bebc1bbcbcd707580c8664bc3ed3f444a0e32de0021' 
  AND token = 'm90HPky83hDFJ4tS7VPx1k9IdJQ9r83oRIwW/tR6zRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}