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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e279e9150522e36929535898348f82841cc47c3b4347233e69b4323fc05a1d' 
  AND token = '7kN6X6WDIu3RMc19PuPuZB+lPicg0OH2CS2a4gtD08s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}