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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0429fff69f7efc2fb7384d523613624e05d0e08f0fe0669cb822b3c4c930bc94' 
  AND token = '5qi0PFuAb+sZDxzqLqA03RpY7g+HE/POQrnxLgUl2QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}