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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a1f9755e66f3dfe911510baa6fff92e85fa846bf0d1a28803627f47334b8443' 
  AND token = '+fBs+To3R2NhgNxh6jigYlgEgdSaSlXF3BTWD1M1x7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}