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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb17f37f6aefad0d2eac369a2d00691407da1617d3c30dec2f6981dc4140bbe3' 
  AND token = 'lhmeooxdgxlfSV0y2wOZVTRYDIxUAaSMaJsQFtKCHS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}