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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '444b77c66d1965c598454cffeafa4aeb22de996634c63adad1b26891bf38ce27' 
  AND token = 'wscaRgI4NCee+12e+It9+YjvinNLrbTYc79UQE1M5cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}