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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c55c9abb70e3876a3088953353f6c1368a16a531ba152450cef2b69139fe54' 
  AND token = 'uc1oFNAZB0MXf/RympFicL+ARsdTXUuUjjdoJ/CoZB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}