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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e19fb23c6da01a4913b09f546b8f81afa68e457e4425de99677aafad2b9bed' 
  AND token = 'mz71af18rhfl8JsZREzds1h7XhGKvHQNecntmSOqPl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}