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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d046c247c267ba645a6cfe62ce8dbc80ca97079a64465315f4acbb551810cd9' 
  AND token = '+D1nUqZE+wVp2PNcSoum1G4/2yKCn3EPanWIj24PXnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}