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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83b5a5c7babc80463e39100ef2dc9e1916f0a5c377b26c8dc5de26b78bed8944' 
  AND token = 'jFDmmeS9PzzL4TGNlujIN4+IN7M2ogvCEMOk5ZVip50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}