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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc419184132f4482c291c9eb0581bf3235a75bca740106d69210d0ea5f975b1a' 
  AND token = '8/K/V+GtiWB1nOZhYO1PEKyucGFmVagONNYelU3tBA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}