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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18c435189b18854c3dfc2e99e20a753c50e4b7392c6b00f77baf74e280bea8cd' 
  AND token = 'CwjDtagr+QTs+YphMrMRb4cP4429d2XVYkWY90GeqxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}