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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2edc67befc542167eda1e72d981c906ba16703865f002ae928fa2f2cc7b98e15' 
  AND token = 'SPix9fr3QTIshtg+6m0Qd0oOKy7vgv14zOhCqC+qEB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}