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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e06914298330048f3aebb3ba6d45c4807b2fb87246e3de815b8a1f773519da9a' 
  AND token = 'PGYc9E1KErI7Zp+Jw/ubxn6CF9JnDZ4WkdaxL3cqPdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}