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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9292988491f704cb25dcc2a2aa88bb80d9c27ebe3672bb96d26f41c447b11bd3' 
  AND token = 's7KGRo0RSjT+Lh+MQhf3fiyGCDbfI6RxIqa5wujTcn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}