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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c4a41525ade44259a159af05832bbc410fa0077d72b2c1856aaed706b0f2660' 
  AND token = 'RA066/diQ2tMg0+Q6FHkkP+Sdu8+iy35D5UN1AtsMaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}