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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd19f7648202e34769e510598fc962734e63d610a7e342d0ae1be39274dc849' 
  AND token = 'Fx01nPVPEpqunm0T142IqIcGHelVMoz01sTSAENAkUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}